Propanediol
AKA “26264-14-2, Propandiol, DTXSID9074939, RefChem:9087, DTXCID7037476, Coupling Lavender Relax Premium massagelotion, Coupling Chamomile Relax Premium massagelotion, 1, 3-PROPANEDIOL (USP-RS), FEMA NO. 4753”
Ingredient
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Ingredient Facts
Propanediol
AKA: 26264-14-2, Propandiol, DTXSID9074939, RefChem:9087, DTXCID7037476, Coupling Lavender Relax Premium massagelotion, Coupling Chamomile Relax Premium massagelotion, 1, 3-PROPANEDIOL (USP-RS), FEMA NO. 4753
Ingredient · Solvent · EWG: 2
Synthetic
Solvent
Clean
Cosmetics and personal care products are not required to be tested for safety before being allowed on the market. The Skin Deep® scoring system was designed to help the public understand whether a product is safe to use or whether it contains ingredients of concern.
Formula
C3H8O2
Mol. Weight
76.09
CAS #
504-63-2, 26264-14-2
Form
Liquid
See origin →
Functions
Solvent
Dissolves other ingredients so they distribute evenly in the formula. Often the invisible "base" everything else is mixed into.
Viscosity Controlling
Dissolves Ingredients
Controls Viscosity
Antioxidant Protection
Reduces Inflammation
Fights Bacteria
Dissolves other ingredients
Controls product thickness
Traditional Use
Developed in the mid-20th century as a synthetic humectant and preservative booster. Created to replace glycerin in industrial and cosmetic applications where a less viscous, more stable moisture-binding agent was needed.
Skin Types
●all-skin-types, gentle
Best For
Dehydration
Pregnancy & Breastfeeding Safe
Yes
3 Piece Classic Suncare Travel Set
COOLA
Age-Defying Fundamentals
Odacité
AHA Exfoliating Solution
Indie Lee
AM + PM Hydrating Booster Set
Goldfaden MD
Anti-aging Dream Duo • SPF 50 + Retinol
Odacité
Anti Aging Eye & Sun Defense Duo
Odacité
Balance + Support Duo
Marie Veronique
The New Tendency Complete Set
Nécessaire
beginner retinol gel 0.1%
Cocokind
Black Tulip Regenerative Brightening Serum
Bloom Effects
Body Surge Travel
Goldfaden MD
Brightening Cleanser Home & Travel Duo
Indie Lee
Brightening Cleanser Travel
Indie Lee
Brightening Cream
Indie Lee
calm & clarify duo
Cocokind
Clean & Comfort Duo
Indie Lee
Clean-ical Formulations AM + PM Serum Duo
Odacité
Clear Skin Oil-Free Moisturizer
COOLA
CoQ-10 Toner Home & Travel Duo
Indie Lee
Daily Acid Toner
Josh Rosebrook
Day & Night Eye Care Duo
Odacité
Day SPF 30 & Night Eye Cream
COOLA
travel-size Electrolyte Water Cream
Cocokind
Detox & Clarify Collection
Goldfaden MD
Detox Hydrating Gel
Goldfaden MD
Double Cleanse for Balanced & Combo Skin
Indie Lee
Double Cleanse for Dry or Mature Skin
Indie Lee
Derm-Restore Super Serum • Edelweiss Extrême® • Peptides + Carnosine
Odacité
Edelweiss Extrême® • Repair + Restore Set
Odacité
Edelweiss Extrême® Skin Barrier Set
Odacité
Everyday Radiance Essentials
Bloom Effects
High Fidelity Balancing Color Corrector
Exa Beauty
High Fidelity Foundation
Exa Beauty
ten18 Lash Amplifying Mascara
Exa Beauty
Free Gift: Botanic Buzz Hand Wash
Ursa Major
Arch Support Brow Sculpt Pomade
Gen See
Gentle Daily Peel
Indie Lee
Golden Hour Body Serum
Ursa Major
holi (sun) spf 50 dewy tinted skin drops
Agent Nateur
holi (soleil) firming & plumping mineral spf 50 sunscreen
Agent Nateur
Hoppin’ Fresh Body Wash
Ursa Major
hydration heroes set
Cocokind
Hydration Set
Kinship
I-Waken Eye Serum
Indie Lee
Super Serum Skin Tint SPF 30
ILIA Beauty
True Skin Serum Concealer
ILIA Beauty
Bronzing Drops
Indie Lee
Air Brow - Tinted
Kosas
BB Burst
Kosas
GrowPotion
Kosas
Safety Assessment of Tromethamine, Aminomethyl Propanediol, and Aminoethyl Propanediol as Used in Cosmetics.
Becker LC, Bergfeld WF, Belsito DV, Hill RA, Klaassen CD et al.
International journal of toxicology, 2018
Safety Assessment of Tromethamine, Aminomethyl Propanediol, and Aminoethyl Propanediol as Used in Cosmetics.
Becker LC, Bergfeld WF, Belsito DV, Hill RA, Klaassen CD et al.
International journal of toxicology, 2018
Final amended report on safety assessment on aminomethyl propanol and aminomethyl propanediol.
Burnett CL, Bergfeld WF, Belsito DV, Klaassen CD, Marks JG Jr et al.
International journal of toxicology, 2009
Final Amended Report on the Safety Assessment of Aminomethyl Propanol and Aminomethyl Propanediol
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Final Report on the Safety Assessment of Aminomethylpropanol and Aminomethylpropanediol
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Safety Assessment of Tromethamine, Aminomethyl Propanediol and Aminoethyl Propanediol as Used in Cosmetics
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Aminoethyl Propanediol
European Commission
EU Cosmetic Ingredient Database (CosIng)
Butyl Ethyl Propanediol
European Commission
EU Cosmetic Ingredient Database (CosIng)
Propanediol
European Commission
EU Cosmetic Ingredient Database (CosIng)
Propanediol Dicaprylate
European Commission
EU Cosmetic Ingredient Database (CosIng)
Propanediol Dicaprylate/Caprate
European Commission
EU Cosmetic Ingredient Database (CosIng)
Propanediol Diisostearate
European Commission
EU Cosmetic Ingredient Database (CosIng)
Propanediol Dipelargonate
European Commission
EU Cosmetic Ingredient Database (CosIng)
Aminoethyl Propanediol
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Aminomethyl Propanediol
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Methylpropanediol
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Propanediol
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Propanediol Dicaprylate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Propanediol Dicaprylate/Caprate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Progress in 1,3-propanediol biosynthesis.
Li B, Gao W, Pan Y, Yao Y, Liu G
Frontiers in bioengineering and biotechnology, 2024
Effects of 1,3-propanediol associated, or not, with butylene glycol and/or glycerol on skin hydration and skin barrier function.
Pinto JR, Monteiro E Silva SA, Leonardi GR
International journal of cosmetic science, 2024
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR