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Pentaerythrityl Tetramyristate
AKA “18641-59-3, Pentaerythritol, tetramyristate, UNII-896NIT9V7W, 896NIT9V7W, Myristic acid, tetraester with pentaerythritol, Tetradecanoic acid, 2, 2-bis(((1-oxotetradecyl)oxy)methyl)-1, 3-propanediyl ester, DTXSID00171901, RefChem:171357, DTXCID2094392”
Emollient
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Ingredient Facts
Pentaerythrityl tetramyristate
AKA: 18641-59-3, Pentaerythritol, UNII-896NIT9V7W, 896NIT9V7W, Myristic acid, Tetraester with pentaerythritol, Tetradecanoic acid, 2, 2-bis(((1-oxotetradecyl)oxy)methyl)-1, 3-propanediyl ester, DTXSID00171901, RefChem:171357, DTXCID2094392
Emollient · Emollient · EWG: 4
Synthetic
Emollient
Skin Conditioner
Not Clean
Tetradecanoic acid, 2,2-bis[(1-oxotetradecyloxy)methyl]-1,3-propanediyl ester
Formula
C61H116O8
Mol. Weight
977.60
CAS #
18641-59-3
Form
Liquid
See origin →
Functions
Emollient
Fills in the tiny cracks between skin cells to make everything feel smooth and soft. The "silky finish" ingredient.
Locks In Moisture
Traditional Use
A synthetic ester developed in the mid-20th century as a cosmetic emollient. Designed to provide lightweight moisture and improve the texture of skincare and makeup formulations without the greasiness of natural oils.
Skin Types
●all-skin-types
Best For
Dryness
Pregnancy & Breastfeeding Safe
Yes
EWG
4
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer
medical-approval
all-shades-safe
Regulatory Status
USA✔ permitted
EU⚠ restricted
JAPAN⚠ restricted
CANADA⚠ restricted
Myristic acid reduces skin inflammation and nociception.
Alonso-Castro AJ, Serrano-Vega R, Pérez Gutiérrez S, Isiordia-Espinoza MA, Solorio-Alvarado CR
Journal of food biochemistry, 2022
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Final Report of the Amended Safety Assessment of Myristic Acid and its Salts and Esters as Used in Cosmetics
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
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Final Report on the Safety Assessment of Oleic Acid, Lauric Acid, Palmitic Acid, Myristic Acid, and Stearic Acid
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
→
Final Report on the Safety Assessment of Pentaerythritol Rosinate (Amended report IJT 17(S4) 1998)
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
→
Methyl Myristic Acid
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Myristic Acid
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Pentaerythrityl Tetramyristate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Myristic Acid
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Allergic contact cheilitis from pentaerythritol rosinate in a lipstick.
Ichihashi K, Soga F, Katoh N, Kishimoto S
Contact dermatitis, 2003
→
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR