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glutathione
AKA “Antioxidant”
Ingredient
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Ingredient Facts
glutathione
AKA: Antioxidant
Ingredient · Reducing · EWG: 1
Synthetic
Amino Acid
Clean
Glycine, N-(N-L-.gamma.-glutamyl-L-cysteinyl)-
Formula
C10H17N3O6S
Mol. Weight
307.33
CAS #
70-18-8
Form
Powder
See origin →
Functions
Reducing
Brightening
Antimicrobial
Antioxidant
Provides scent
Chemical reduction
Traditional Use
This appears to be a CAS number without a standard cosmetic INCI name; unable to provide historical context without clarification of the specific ingredient.
Skin Types
●all-skin-types, gentle
Best For
General
EWG
1
CIR
Insufficient
Pregnancy
—
CIR Safety Findings
ewg-1
pregnancy-nursing-safe
all-shades-safe
Regulatory Status
USAunder review
CANADA✔ permitted
Regulatory Agencies
Fruit-based Natural Antioxidants in Meat and Meat Products: A Review.
Ahmad SR, Gokulakrishnan P, Giriprasad R, Yatoo MA
Critical reviews in food science and nutrition, 2015
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Fruit-based Natural Antioxidants in Meat and Meat Products: A Review.
Ahmad SR, Gokulakrishnan P, Giriprasad R, Yatoo MA
Critical reviews in food science and nutrition, 2015
→
Fruit-based Natural Antioxidants in Meat and Meat Products: A Review.
Ahmad SR, Gokulakrishnan P, Giriprasad R, Yatoo MA
Critical reviews in food science and nutrition, 2015
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Evaluation of the anti-aging and antioxidant action of An...
Mulkah Olufemi Ajagun-Ogunleye, Osaretin Albert Taiwo Ebuehi
Journal of food biochemistry, 2020
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Green and eco-friendly biosynthesis of zinc oxide nanoparticles using Calendula officinalis flower extract: Wound healing potential and antioxidant ac
Aydin Acar C, Gencer MA, Pehlivanoglu S, Yesilot S, Donmez S
International wound journal, 2024
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Green and eco-friendly biosynthesis of zinc oxide nanoparticles using Calendula officinalis flower extract: Wound healing potential and antioxidant ac
Aydin Acar C, Gencer MA, Pehlivanoglu S, Yesilot S, Donmez S
International wound journal, 2024
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Antioxidant and anti-inflammatory effect of olive leaf ex...
Mehmet Berköz, Tahir Kahraman, Zwain Nozad Shamsulddin, Mirosław Krośniak
Journal of basic and clinical physiology and pharmacology, 2023
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Cocoa and Grape Seed Byproducts as a Source of Antioxidant and Anti-Inflammatory Proanthocyanidins.
Cádiz-Gurrea ML, Borrás-Linares I, Lozano-Sánchez J, Joven J, Fernández-Arroyo S et al.
International journal of molecular sciences, 2017
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Melanogenesis Inhibitory and Antioxidant Effects of Camellia oleifera Seed Oil.
Chaikul P, Sripisut T, Chanpirom S, Sathirachawan K, Ditthawuthikul N
Advanced pharmaceutical bulletin, 2017
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Antioxidant activities of chitobiose and chitotriose.
Chen AS, Taguchi T, Sakai K, Kikuchi K, Wang MW et al.
Biological & pharmaceutical bulletin, 2003
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Antioxidant activities of chitobiose and chitotriose.
Chen AS, Taguchi T, Sakai K, Kikuchi K, Wang MW et al.
Biological & pharmaceutical bulletin, 2003
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Antioxidant, Anti-Inflammatory and Attenuating Intracellular Reactive Oxygen Species Activities of Nicotiana tabacum var. Virginia Leaf Extract Phytos
Chittasupho C, Chaobankrang K, Sarawungkad A, Samee W, Singh S et al.
Gels (Basel, Switzerland), 2023
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Nomilin from Yuzu Seed Has In Vitro Antioxidant Activity and Downregulates Melanogenesis in B16F10 Melanoma Cells through the PKA/CREB Signaling Pathw
Choi MH, Yang SH, Kim ND, Shin HJ
Antioxidants (Basel, Switzerland), 2022
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Nomilin from Yuzu Seed Has In Vitro Antioxidant Activity and Downregulates Melanogenesis in B16F10 Melanoma Cells through the PKA/CREB Signaling Pathw
Choi MH, Yang SH, Kim ND, Shin HJ
Antioxidants (Basel, Switzerland), 2022
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Nomilin from Yuzu Seed Has In Vitro Antioxidant Activity and Downregulates Melanogenesis in B16F10 Melanoma Cells through the PKA/CREB Signaling Pathw
Choi MH, Yang SH, Kim ND, Shin HJ
Antioxidants (Basel, Switzerland), 2022
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Chemical Composition and Bioactivity of Nelumbo nucifera Gaertn. Flower Extract Fractions: In Vitro Antioxidant and Anti-Inflammatory Properties.
Choo JH, Lee SY, Min K, Kang NG
Current issues in molecular biology, 2025
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Chemical Composition and Bioactivity of Nelumbo nucifera Gaertn. Flower Extract Fractions: In Vitro Antioxidant and Anti-Inflammatory Properties.
Choo JH, Lee SY, Min K, Kang NG
Current issues in molecular biology, 2025
→
glutathione
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Systematic review and technological prospection: ethyl ferulate, a phenylpropanoid with antioxidant and neuroprotective actions.
Cunha FVM, Coelho AG, Azevedo PSDS, da Silva AA Júnior, Oliveira FA et al.
Expert opinion on therapeutic patents, 2019
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Scalp application of antioxidants improves scalp condition and reduces hair shedding in a 24-week randomized, double-blind, placebo-controlled clinica
Davis MG, Piliang MP, Bergfeld WF, Caterino TL, Fisher BK et al.
International journal of cosmetic science, 2021
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The anti-inflammatory and antioxidant properties of 1,2-decanediol and willow bark extract in lipopolysaccharide-stimulated keratinocytes.
Di Caprio R, Monfrecola G, Balato A, Balato N, Gasparri F et al.
Giornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia, 2019
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Engineering Yarrowia lipolytica for the Synthesis of Glutathione from Organic By-Products.
Do DTH, Fickers P
Microorganisms, 2020
→
FSP1 is a glutathione-independent ferroptosis suppressor.
Doll S, Freitas FP, Shah R, Aldrovandi M, da Silva MC et al.
Nature, 2019
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FSP1 is a glutathione-independent ferroptosis suppressor.
Doll S, Freitas FP, Shah R, Aldrovandi M, da Silva MC et al.
Nature, 2019
→
glutathione
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Developing antioxidant-antimicrobial nanofibers containing Corallina officinalis extract for wound healing.
Fahmy AM, Soliman AM, Fahmy SR, Bayoumi Ali S, Sadek SA
Journal of biomaterials science. Polymer edition, 2026
→
Chemical characterization of Eucalyptus (Eucalyptus globulus) leaf essential oil and evaluation of its antifungal, antibacterial and antioxidant activ
Haj Moussa H, Sara B, Benhalima H, Benaliouche F, Sbartai I et al.
Cellular and molecular biology (Noisy-le-Grand, France), 2025
→
Aloe vera (L.) Webb.: Natural Sources of Antioxidants - A Review.
Hęś M, Dziedzic K, Górecka D, Jędrusek-Golińska A, Gujska E
Plant foods for human nutrition (Dordrecht, Netherlands), 2019
→
Eco-friendly sunscreen formulation based on starches and PEG-75 lanolin increases the antioxidant capacity and the light scattering activity in the vi
Infante VHP, Lohan SB, Schanzer S, Campos PMBGM, Lademann J et al.
Journal of photochemistry and photobiology. B, Biology, 2021
→
Antioxidant activity of gamma-oryzanol: mechanism of action and its effect on oxidative stability of pharmaceutical oils.
Juliano C, Cossu M, Alamanni MC, Piu L
International journal of pharmaceutics, 2005
→
Effects of antioxidant polyphenols on TNF-alpha-related diseases.
Kawaguchi K, Matsumoto T, Kumazawa Y
Current topics in medicinal chemistry, 2011
→
Effects of antioxidant polyphenols on TNF-alpha-related diseases.
Kawaguchi K, Matsumoto T, Kumazawa Y
Current topics in medicinal chemistry, 2011
→
Effects of antioxidant polyphenols on TNF-alpha-related diseases.
Kawaguchi K, Matsumoto T, Kumazawa Y
Current topics in medicinal chemistry, 2011
→
Antioxidant effects of phenolic compounds in through the distillation of Lonicera japonica & Chenpi extract and anti-inflammation on skin keratinocyte
Kim HH, Jeong SH, Park MY, Bhosale PB, Abusaliya A et al.
Scientific reports, 2023
→
Antioxidant effects of phenolic compounds in through the distillation of Lonicera japonica & Chenpi extract and anti-inflammation on skin keratinocyte
Kim HH, Jeong SH, Park MY, Bhosale PB, Abusaliya A et al.
Scientific reports, 2023
→
Antioxidant effects of phenolic compounds in through the distillation of Lonicera japonica & Chenpi extract and anti-inflammation on skin keratinocyte
Kim HH, Jeong SH, Park MY, Bhosale PB, Abusaliya A et al.
Scientific reports, 2023
→
Antioxidant effects of phenolic compounds in through the distillation of Lonicera japonica & Chenpi extract and anti-inflammation on skin keratinocyte
Kim HH, Jeong SH, Park MY, Bhosale PB, Abusaliya A et al.
Scientific reports, 2023
→
Facile Fabrication of α-Bisabolol Nanoparticles with Improved Antioxidant and Antibacterial Effects.
Kim S, Yu S, Kim J, Khaliq NU, Choi WI et al.
Antioxidants (Basel, Switzerland), 2023
→
Antioxidants for Skin Health.
Virender Kumar, Neha Tanwar, Muskan Goel, Mohit Khan, Davinder Kumar, Gajendra Singh + 3 more
Recent advances in food, nutrition & agriculture, 2025
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Enhanced Antioxidant and Protective Effects of Fermented Solanum melongena L. Peel Extracts Against Ultraviolet B-Induced Skin Damage.
Lee JH, Kim J, Jo YC, Jo YH, Jeong YH et al.
Nutrients, 2025
→
Preparation of dual supramolecular EGCG-carboxymethyl chitosan: Structure, antioxidant and anti-inflammatory properties.
Lu B, Fu Y, Liu Y, Zhang Z, Chen Y et al.
International journal of biological macromolecules, 2025
→
A novel fullerene composite material for directional oil control and antioxidant.
Lu WW, Xu Z, Cheng J, Zhang T, Liao XD et al.
Journal of cosmetic dermatology, 2024
→
Microwave-Assisted Extraction of Phenolic Compounds and Antioxidants for Cosmetic Applications Using Polyol-Based Technology.
Myat Win S, Saelee M, Myo H, Khat-Udomkiri N
Journal of visualized experiments : JoVE, 2024
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Microwave-Assisted Extraction of Phenolic Compounds and Antioxidants for Cosmetic Applications Using Polyol-Based Technology.
Myat Win S, Saelee M, Myo H, Khat-Udomkiri N
Journal of visualized experiments : JoVE, 2024
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Probiotic-mediated blueberry (Vaccinium corymbosum L.) fruit fermentation to yield functionalized products for augmented antibacterial and antioxidant
Oh BT, Jeong SY, Velmurugan P, Park JH, Jeong DY
Journal of bioscience and bioengineering, 2017
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Variation in antioxidant capacity, antioxidant activity and mineral composition during flower development of oil-bearing rose (Rosa damascena Mill.).
Önder D
Scientific reports, 2023
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Comparing the effects of mitochondrial targeted and localized antioxidants with cellular antioxidants in human skin cells exposed to UVA and hydrogen
Oyewole AO, Wilmot MC, Fowler M, Birch-Machin MA
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2014
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A Proprietary Punica granatum pericarp Extract, Its Antioxidant Properties Using Multi-Radical Assays and Protection Against UVA-Induced Damages in a
Pannakal ST, Durand S, Gizard J, Sextius P, Planel E et al.
Antioxidants (Basel, Switzerland), 2025
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Quality Characteristics and Antioxidant Potential of Lemon (Citrus limon Burm. f.) Seed Oil Extracted by Different Methods.
Park YS, Kim ID, Dhungana SK, Park EJ, Park JJ et al.
Frontiers in nutrition, 2021
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Antioxidant and Antiaging Properties of Agar Obtained from Brown Seaweed Laminaria digitata (Hudson) in D-Galactose-Induced Swiss Albino Mice.
Reshma BS, Aavula T, Narasimman V, Ramachandran S, Essa MM et al.
Evidence-based complementary and alternative medicine : eCAM, 2022
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Gallic Acid: A Potent Antioxidant and Anti-inflammatory A...
Urvashi Saini, Anjali Sharma, Vishnu Mittal
Recent advances in drug delivery and formulation, 2026
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Antioxidant capacity, phenolic content, and profiling of phenolic compounds in the seeds, skin, and pulp of Vitis rotundifolia (Muscadine Grapes) As d
Sandhu AK, Gu L
Journal of agricultural and food chemistry, 2010
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Shoot Cultures of Vitis vinifera (Vine Grape) Different Cultivars as a Promising Innovative Cosmetic Raw Material-Phytochemical Profiling, Antioxidant
Sharafan M, Malinowska MA, Kubicz M, Kubica P, Gémin MP et al.
Molecules (Basel, Switzerland), 2023
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Antioxidant and Anti-Melanogenesis Effects of Colloidal Gold Camellia sinensis L. Extracts.
Shin S, Kim M, Song N, Sun S, Choi J et al.
Molecules (Basel, Switzerland), 2022
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Effects of antioxidant capacity-based dietary replacement of vitamin E with commercial products containing grape skin-green tea extracts or hydrolyzed
Simoni M, Danese T, Mezzasalma N, Goi A, Pitino R et al.
Frontiers in veterinary science, 2025
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Flavonoid antioxidant silymarin and skin cancer.
Rana P Singh, Rajesh Agarwal
Antioxidants & redox signaling, 2002
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Flavonoid antioxidant silymarin and skin cancer.
Rana P Singh, Rajesh Agarwal
Antioxidants & redox signaling, 2002
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Glutathione as a skin whitening agent: Facts, myths, evid...
Sidharth Sonthalia, Deepashree Daulatabad, Rashmi Sarkar
Indian journal of dermatology, venereology and leprology, 2016
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Glutathione as a skin whitening agent: Facts, myths, evid...
Sidharth Sonthalia, Deepashree Daulatabad, Rashmi Sarkar
Indian journal of dermatology, venereology and leprology, 2016
→
Glutathione as a skin whitening agent: Facts, myths, evid...
Sidharth Sonthalia, Deepashree Daulatabad, Rashmi Sarkar
Indian journal of dermatology, venereology and leprology, 2016
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Glutathione as a skin whitening agent: Facts, myths, evidence and controversies.
Sonthalia S, Daulatabad D, Sarkar R
Indian journal of dermatology, venereology and leprology, 2016
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Antimicrobial Nanoparticles Composed of Zein and Arginine-Phenylalanine-Based Surfactants for Wound Related Infections: Antioxidant and Skin-Related A
Sousa FFO, Hafidi Z, García MT, Moran MDC, Vazquez S et al.
Antibiotics (Basel, Switzerland), 2024
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Chemical Composition and Antioxidant Properties of Oils from the Seeds of Five Apricot (Prunus armeniaca L.) Cultivars.
Stryjecka M, Kiełtyka-Dadasiewicz A, Michalak M, Rachoń L, Głowacka A
Journal of oleo science, 2019
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Phytosteryl sinapates and vanillates: chemoenzymatic synthesis and antioxidant capacity assessment.
Tan Z, Shahidi F
Food chemistry, 2013
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Phytosteryl sinapates and vanillates: chemoenzymatic synthesis and antioxidant capacity assessment.
Tan Z, Shahidi F
Food chemistry, 2013
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Phytosteryl sinapates and vanillates: chemoenzymatic synthesis and antioxidant capacity assessment.
Tan Z, Shahidi F
Food chemistry, 2013
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Antioxidant screening and phenolic content of ethanol extracts of selected Baja California Peninsula macroalgae.
Tenorio-Rodriguez PA, Murillo-Álvarez JI, Campa-Cordova ÁI, Angulo C
Journal of food science and technology, 2017
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Esculin and ferric citrate-incorporated sturgeon skin gelatine as an antioxidant film for food packaging to prevent Enterococcus faecalis contaminatio
Tian L, Liang C, Fu C, Qiang T, Liu Y et al.
Food & function, 2020
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Highly galloylated tannin fractions from witch hazel (Hamamelis virginiana) bark: electron transfer capacity, in vitro antioxidant activity, and effec
Touriño S, Lizárraga D, Carreras A, Lorenzo S, Ugartondo V et al.
Chemical research in toxicology, 2008
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Unseparated Olive Pruning Waste as a Sustainable Feedstock: DoE-Optimized Extracts with Antioxidant Activity Equivalent to Isolated Leaves.
Tumminelli E, Cavalloro V, Ratto D, Marrubini G, Martino E et al.
Antioxidants (Basel, Switzerland), 2025
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Validation of a High-Performance Liquid Chromatography with Photodiode Array Detection Method for the Separation and Quantification of Antioxidant and
Tungmunnithum D, Drouet S, Hano C
Molecules (Basel, Switzerland), 2022
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Cyanobacteria and Red Macroalgae as Potential Sources of Antioxidants and UV Radiation-Absorbing Compounds for Cosmeceutical Applications.
Vega J, Bonomi-Barufi J, Gómez-Pinchetti JL, Figueroa FL
Marine drugs, 2020
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Cyanobacteria and Red Macroalgae as Potential Sources of Antioxidants and UV Radiation-Absorbing Compounds for Cosmeceutical Applications.
Vega J, Bonomi-Barufi J, Gómez-Pinchetti JL, Figueroa FL
Marine drugs, 2020
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Metabolomic profiling of wild rooibos (Aspalathus linearis) ecotypes and their antioxidant-derived phytopharmaceutical potential.
Wilkinson C, Brooks J, Stander MA, Malgas R, Roodt-Wilding R et al.
Metabolomics : Official journal of the Metabolomic Society, 2024
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Bioinspired Bilayer Nanofibrous Membrane with Unidirectional Water Transport, Antimicrobial Properties, Antioxidant Capacity, and pH-Responsive Epigal
Xia Z, Shang S, Zhang J, Ding Z, Li X et al.
Langmuir : the ACS journal of surfaces and colloids, 2025
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Antioxidant Effects of Essential Oils from the Peels of Citrus Cultivars.
Yang J, Park MJ
Molecules (Basel, Switzerland), 2025
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Isolation and identification of an antioxidant flavonoid compound from citrus-processing by-product.
Yang X, Kang SM, Jeon BT, Kim YD, Ha JH et al.
Journal of the science of food and agriculture, 2011
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Isolation and identification of an antioxidant flavonoid compound from citrus-processing by-product.
Yang X, Kang SM, Jeon BT, Kim YD, Ha JH et al.
Journal of the science of food and agriculture, 2011
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Antioxidant Properties of Ferulic Acid and Its Possible Application.
Zduńska K, Dana A, Kolodziejczak A, Rotsztejn H
Skin pharmacology and physiology, 2018
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Screening and preparation of highly active antioxidant peptides of apricot and their inhibitory effect on ultraviolet radiation.
Zhu X, Zhang X, Wang Z, Ren F, Zhu X et al.
Food chemistry, 2025
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Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR