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Dioctyl Sodium Sulfosuccinate
AKA “Sodium dioctyl sulfosuccinate, Sodium di-n-octyl sulfosuccinate, Dioctyl sodiosulfosuccinate, Sodium bis(octyl)sulfosuccinate, DTXSID7041881, Sodium O, O-dioctylsulfosuccinic acid, Sodium sulfosuccinic acid dioctyl ester, Sulfosuccinic acid 1, 4-dioctyl ester sodium salt, Dioctyl sulfosuccinate, sodium salt, RefChem:1083745”
Ingredient
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Ingredient Facts
Dioctyl sodium sulfosuccinate
AKA: Sodium dioctyl sulfosuccinate, Sodium di-n-octyl sulfosuccinate, Dioctyl sodiosulfosuccinate, Sodium bis(octyl)sulfosuccinate, DTXSID7041881, Sodium O, O-dioctylsulfosuccinic acid, Sodium sulfosuccinic acid dioctyl ester, Sulfosuccinic acid 1, 4-dioctyl ester sodium salt, Dioctyl sulfosuccinate, Sodium salt, RefChem:1083745
Ingredient · Absorbent · EWG: 1
Synthetic
Clean
The CIR Expert Panel concluded that the following 8 dialkyl sulfosuccinate salts are safe in the present practices of use and concentration in cosmetics in this safety assessment when formulated to be non-irritating...Dicapryl Sodium Sulfosuccinate...
Formula
C20H37NaO7S
Mol. Weight
444.60
CAS #
1639-66-3
Form
Liquid
State
Dioctyl sodium sulfosuccinate is an odorless colorless to white waxy solid. Sinks and mixes slowly with water. (USCG, 1999)
See origin →
Functions
Absorbent
Viscosity Controlling
Antioxidant Protection
Locks In Moisture
Fights Bacteria
Traditional Use
A synthetic surfactant and emulsifier developed in the mid-20th century. Used in cleansing products as a gentle detergent; no traditional medicinal use.
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Yes
EWG
1
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer
medical-approval
all-shades-safe
Regulatory Status
USA✔ permitted
EU⚠ restricted
JAPAN⚠ restricted
CANADA⚠ restricted
Effects of Sodium Salts of Fatty Acids and Their Derivatives on Skin Permeation of Cromolyn Sodium.
Akinbote OE, Verana G, Dandekar AA, Tijani AO, Mishra D et al.
AAPS PharmSciTech, 2023
→
Effects of Sodium Salts of Fatty Acids and Their Derivatives on Skin Permeation of Cromolyn Sodium.
Akinbote OE, Verana G, Dandekar AA, Tijani AO, Mishra D et al.
AAPS PharmSciTech, 2023
→
Amended Final Report on the Safety Assessment of Dioctyl Sodium Sulfosuccinate
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
→
Disodium Oleth-3 Sulfosuccinate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Disodium Oleyl Phosphate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Sodium Octoxynol-2 Ethane Sulfonate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Sodium Octoxynol-2 Sulfate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Sodium Octoxynol-6 Sulfate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Sodium Octoxynol-9 Sulfate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Sodium Oleate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Sodium Oleoyl Isethionate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Sodium Oleoyl Lactylate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Sodium Oleoyl Sarcosinate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Sodium Oleth Sulfate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Sodium Oleyl Methyl Isethionate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Sodium Oleyl Sulfate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Sodium Olivamphoacetate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Sodium Olivate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Sodium Olivoyl Glutamate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Sodium Oxidized Starch Acetate/Succinate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Dioctyl Sodium Sulfosuccinate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Sodium Oleate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Sodium Oleth Sulfate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Sodium Olivamphoacetate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Sodium Olivate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Sodium Olivoyl Glutamate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
SODIUM SALT
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
The surfactant Dioctyl Sodium Sulfosuccinate (DOSS) exposure causes adverse effects in embryos and adults of zebrafish (Danio rerio).
González-Penagos CE, Zamora-Briseño JA, Améndola-Pimenta M, Pérez-Vega JA, Montero-Muñoz J et al.
Toxicology and applied pharmacology, 2022
→
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR