Ceramide 2
AKA “CERAMIDE NG, n-stearoyl dihydrosphingosine, Ceramide NS, Ceramide 2 pure, (2S, 3R)-2-(Octadecanoylamino)octadecane-1
Skin Conditioning
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Ingredient Facts
Ceramide 2
AKA: CERAMIDE NG, N-stearoyl dihydrosphingosine, Ceramide NS, Ceramide 2 pure, (2S, 3R)-2-(Octadecanoylamino)octadecane-1
Skin Conditioning · Hair Conditioning · EWG: 4
Synthetic
Skin Conditioner
Hair Care
Ceramide
Not Clean
Ceramide 2 (Retired) is the N-acylated sphingolipid having the erythro structure that conforms generally to the formula, where m has a value ranging from 14 to 28 and n has a value ranging from 10 to 16.The INCI Name, Ceramide 2, originally developed in 1997, was designated with a retired status in 2014. For an interim period of time, trade name assignments formerly published with the INCI Name Ceramide 2 will be retained in the retired monograph, and also published with the new name assignment
Formula
C36H71NO4
Mol. Weight
582.0
CAS #
100403-19-8
Form
Liquid
See origin →
Functions
Hair Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Strengthens skin barrier
Locks in moisture
Prevents moisture loss
Traditional Use
Discovered as part of the skin's lipid matrix research in the 1980s-1990s. Ceramide 2 is synthetically manufactured to replicate this abundant natural skin ceramide for barrier function restoration.
Skin Types
all-skin-types
Best For
Dryness
Pregnancy & Breastfeeding Safe
Yes
EWG
4
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer
medical-approval
all-shades-safe
Regulatory Status
USApermitted
EUrestricted
JAPANrestricted
CANADArestricted
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR