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C32-36 Isoalkyl Acid
AKA “Isoalkyl Acid, Fatty Acid”
Acid
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Ingredient Facts
C32-36 isoalkyl acid
AKA: Fatty Acid
Acid · Skin Conditioning · EWG: 4
Synthetic
Skin Conditioner
Barrier Lipid
Acid
Not Clean
C32-36 Isoalkyl Acid is a mixture of branched, saturated fatty acids with 32 to 36 carbons in the alkyl chain, isolated from Lanolin Acid
CAS #
68201-22-9
Form
Liquid
State
Solid
See origin →
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Locks in moisture
Traditional Use
A synthetic branched-chain fatty acid developed for cosmetic formulations as a conditioning and emollient agent, offering stability advantages over natural fatty acids.
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Yes
EWG
4
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer
medical-approval
all-shades-safe
Regulatory Status
USA✔ permitted
EU⚠ restricted
JAPAN⚠ restricted
CANADA⚠ restricted
Occupational allergic contact dermatitis caused by coconut fatty acids diethanolamide.
Aalto-Korte K, Pesonen M, Kuuliala O, Suuronen K
Contact dermatitis, 2014
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Occupational allergic contact dermatitis caused by coconut fatty acids diethanolamide.
Aalto-Korte K, Pesonen M, Kuuliala O, Suuronen K
Contact dermatitis, 2014
→
Occupational allergic contact dermatitis caused by coconut fatty acids diethanolamide.
Aalto-Korte K, Pesonen M, Kuuliala O, Suuronen K
Contact dermatitis, 2014
→
Effects of Sodium Salts of Fatty Acids and Their Derivatives on Skin Permeation of Cromolyn Sodium.
Akinbote OE, Verana G, Dandekar AA, Tijani AO, Mishra D et al.
AAPS PharmSciTech, 2023
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Effects of Sodium Salts of Fatty Acids and Their Derivatives on Skin Permeation of Cromolyn Sodium.
Akinbote OE, Verana G, Dandekar AA, Tijani AO, Mishra D et al.
AAPS PharmSciTech, 2023
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Dietary influences of evening primrose and fish oil on the skin of essential fatty acid-deficient guinea pigs.
Chapkin RS, Ziboh VA, McCullough JL
The Journal of nutrition, 1987
→
Final Report: Safety Assessment of Fatty Acids and Fatty Acid Salts as Used in Cosmetics
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
→
Safety Assessment of Fatty Acid Amidopropyl Dimethylamines as Used in Cosmetics
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
→
Safety Assessment of Plant-Derived Fatty Acid Oils
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
→
Safety Assessment of Polyglyceryl Fatty Acid Esters as Used in Cosmetics
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
→
Safety Assessment of Tripeptide-1, Hexapeptide-12 Their Metal Salts and Fatty Acid Derivatives, and Palmitoyl Tetrapeptide-7 as Used in Cosmetics
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
→
C10-40 Isoalkyl Acid
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
C10-40 Isoalkyl Acid Octyldodecanol Esters
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
C10-40 Isoalkyl Acid Phytosterol Esters
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
C10-40 Isoalkyl Acid Triglyceride
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
C14-28 Isoalkyl Acid
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
C32-36 Isoalkyl Acid
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Ethylhexyl C10-40 Isoalkyl Acidate
European Commission
EU Cosmetic Ingredient Database (CosIng)
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Dietary olive oil intake aggravates psoriatic skin inflammation in mice via Nrf2 activation and polyunsaturated fatty acid imbalance.
Donato-Trancoso A, Correa Atella G, Romana-Souza B
International immunopharmacology, 2022
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C14-28 Isoalkyl Acid
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
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A comparison of the physicochemical properties and fatty acid composition of indaiá (Attalea dubia) and Babassu (Orbignya phalerata) oils.
Ferreira BS, Faza LP, Le Hyaric M
TheScientificWorldJournal, 2012
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Detection of fatty acid ethyl esters in skin surface lipids as biomarkers of ethanol consumption in alcoholics, social drinkers, light drinkers, and t
González-Illán F, Ojeda-Torres G, Díaz-Vázquez LM, Rosario O
Journal of analytical toxicology, 2011
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Eye and skin irritation tests on the rabbit of several fatty acid esters.
Guillot JP, Giauffret JY, Martini MC, Gonnet JF, Soulé G
International journal of cosmetic science, 1979
→
Eye and skin irritation tests on the rabbit of several fatty acid esters.
Guillot JP, Giauffret JY, Martini MC, Gonnet JF, Soulé G
International journal of cosmetic science, 1979
→
Eye and skin irritation tests on the rabbit of several fatty acid esters.
Guillot JP, Giauffret JY, Martini MC, Gonnet JF, Soulé G
International journal of cosmetic science, 1979
→
Eye and skin irritation tests on the rabbit of several fatty acid esters.
Guillot JP, Giauffret JY, Martini MC, Gonnet JF, Soulé G
International journal of cosmetic science, 1979
→
The effect of dietary camelina, flaxseed, and canola oil supplementation on skin fatty acid profile and immune and inflammatory responses in healthy a
Hartwig S, Burron S, Richards T, Rankovic A, Ma DWL et al.
Journal of animal science, 2025
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Cosmetic and Therapeutic Applications of Fish Oil's Fatty Acids on the Skin.
Huang TH, Wang PW, Yang SC, Chou WL, Fang JY
Marine drugs, 2018
→
Effect of dietary supplementation with omega-3 fatty acid...
Jae Yoon Jung, Hyuck Hoon Kwon, Jong Soo Hong, Ji Young Yoon, Mi Sun Park, Mi Young Jang + 1 more
Acta dermato-venereologica, 2014
→
Effect of dietary supplementation with omega-3 fatty acid...
Jae Yoon Jung, Hyuck Hoon Kwon, Jong Soo Hong, Ji Young Yoon, Mi Sun Park, Mi Young Jang + 1 more
Acta dermato-venereologica, 2014
→
Borage oil restores acidic skin pH by up-regulating the activity or expression of filaggrin and enzymes involved in epidermal lactate, free fatty acid
Kim KP, Jeon S, Kim MJ, Cho Y
Nutrition research (New York, N.Y.), 2018
→
Borage oil restores acidic skin pH by up-regulating the activity or expression of filaggrin and enzymes involved in epidermal lactate, free fatty acid
Kim KP, Jeon S, Kim MJ, Cho Y
Nutrition research (New York, N.Y.), 2018
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Genetic inactivation of the Carnitine/Acetyl-Carnitine mitochondrial carrier of Yarrowia lipolytica leads to enhanced odd-chain fatty acid production.
Messina E, de Souza CP, Cappella C, Barile SN, Scarcia P et al.
Microbial cell factories, 2023
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Fatty acid sulphoalkyl amides and esters as cosmetic surfactants.
Petter PJ
International journal of cosmetic science, 1984
→
Fatty acid sulphoalkyl amides and esters as cosmetic surfactants.
Petter PJ
International journal of cosmetic science, 1984
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Polyglycerol fatty acid ester surfactant-based microemulsions for targeted delivery of ceramide AP into the stratum corneum: formulation, characterisa
Sahle FF, Metz H, Wohlrab J, Neubert RH
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2012
→
The essential fatty acids.
Sardesai VM
Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition, 1992
→
Fatty acid composition and productive traits of broiler fed diets containing conjugated linoleic acid.
Sirri F, Tallarico N, Meluzzi A, Franchini A
Poultry science, 2003
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In vitro human skin barrier modulation by fatty acids: skin permeation and thermal analysis studies.
Tanojo H, Bouwstra JA, Junginger HE, Boddé HE
Pharmaceutical research, 1997
→
Screening of fatty acids, saccharides, and phytochemicals in Jatropha curcas seed kernel as their trimethylsilyl derivatives using gas chromatography/
Thi HT, Le BA, Le HNT, Okitsu K, Imamura K et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2018
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Verified Jun 2026
Data: CosIng · EWG · CIR