Bisabolol
AKA “515-69-5, 36HQN158VC, DTXSID5045964, DTXCID3025964, 5-HEPTEN-2-OL, 6-METHYL-2-(4-METHYL-3-CYCLOHEXEN-1-YL)-, 3-Cyclohexene-1-methanol, alpha, 4-dimethyl-alpha-(4-methyl-3-pentenyl)-, (alphaR, 1R)-rel-, (R*, R*)-, 4-dimethyl-alpha-(4-methyl-3-penten-1-yl)-, GZE Skincare Oil”
Synthetic
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Ingredient Facts
Bisabolol
AKA: 515-69-5, 36HQN158VC, DTXSID5045964, DTXCID3025964, 5-HEPTEN-2-OL, 6-METHYL-2-(4-METHYL-3-CYCLOHEXEN-1-YL)-, 3-Cyclohexene-1-methanol, Alpha, 4-dimethyl-alpha-(4-methyl-3-pentenyl)-, (alphaR, 1R)-rel-, (R*, R*)-, 4-dimethyl-alpha-(4-methyl-3-penten-1-yl)-, GZE Skincare Oil
Synthetic · Skin Conditioning · EWG: 2
Synthetic
Skin Conditioner
Synthetic
Clean
monocyclic sesquiterpene alcohol with strong bacteriocidal effects, especilly against M. Tuberc.; isolated from seed plant Populus tacamacaha; RN given refers to cpd without isomeric desigation
Solubility Practically insoluble or insoluble in water
Formula
C15H26O
Mol. Weight
222.37
CAS #
515-69-5, 23089-26-1
Form
Powder
State
Clear colourless liquid; Fruity nutty aroma with hints of coconut
See origin →
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Quells irritation
Traditional Use
The CAS number for Glycerin, an alcohol compound first isolated from fats in the early 19th century. Widely used in traditional and modern cosmetics as a humectant and skin softener.
Skin Types
●all-skin-types
Best For
General
3 Piece Classic Suncare Travel Set
COOLA
Black Tulip Eye Treatment
Bloom Effects
Hydrating Sunscreen Lotion - Peach Blossom
COOLA
Face Sunscreen Mist
COOLA
Original Liplux® Lip Balm Sunscreen
COOLA
Everyday Radiance Essentials
Bloom Effects
holi (sun) spf 50 dewy tinted skin drops
Agent Nateur
holi (soleil) firming & plumping mineral spf 50 sunscreen
Agent Nateur
Hydration Set
Kinship
I-Waken Eye Serum
Indie Lee
Lip Wrap Reviving Balm
ILIA Beauty
Super Serum Skin Tint SPF 30
ILIA Beauty
lactic acid cleanser duo
Agent Nateur
Lunar Bloom Retinal Serum
Ursa Major
Making Moves Milky Cleanser
Ursa Major
Zinc Oxide Sunscreen Lotion - Tropical Coconut
COOLA
Zinc Oxide Sunscreen Spray - Mineral
COOLA
Blurring Blot Balm & Primer
MOB Beauty
Blurring Ceramide Cream Foundation
MOB Beauty
Blush
MOB Beauty
Blush Last Call
MOB Beauty
Bronzer
MOB Beauty
Cake Liner
MOB Beauty
Cake Liner Last Call
MOB Beauty
Cream Clay Blush
MOB Beauty
Cream Clay Blush Last Call
MOB Beauty
Cream Clay Bronzer
MOB Beauty
Eyeshadow Last Call
MOB Beauty
Frost Lipstick
MOB Beauty
Hyaluronic Highlight Balm
MOB Beauty
Hyaluronic Highlight Balm Last Call
MOB Beauty
Hydrating Shine Lip Balm
MOB Beauty
Smooth Precision Waterproof Lip Liner
MOB Beauty
Soft Matte Lipstick
MOB Beauty
Soft Matte Lipstick Last Call
MOB Beauty
Suspended Sparkle Balm
MOB Beauty
Suspended Sparkle Balm Last Call
MOB Beauty
The Neutrals Eye Essentials Palette
MOB Beauty
Volumizing Mascara
MOB Beauty
Morning + Night Serum Set
Kinship
Radiance Reset
Bloom Effects
Refreshing Water Cream
COOLA
Restorative Body Serum - Vanilla
Kinship
ReFresh Eye Brightener Broad Spectrum SPF 30 + Correcting Tint
RMS Beauty
SunCoverup Super Tint SPF 50
RMS Beauty
Bestsellers Bundle
Saie
Complexion Boost
Saie
Skin Glow Duo
Saie
Slip Brush Duo
Saie
Slip Tint™ Tinted Moisturizer
Saie
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Fragrance material review on dihydro-alpha-terpineol.
Bhatia SP, McGinty D, Letizia CS, Api AM
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2008
Final Report on the Safety Assessment of Bisabolol
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Final Report on the Safety Assessment of Sodium Alpha-Olefin Sulfonates
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Safety Assessment of alpha-Amino Acids as Used in Cosmetics
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Sodium alpha-Olefin Sulfonates
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Alpha-Isomethyl Ionone
European Commission
EU Cosmetic Ingredient Database (CosIng)
Thioctic (Alpha Lipoic) Acid
European Commission
EU Cosmetic Ingredient Database (CosIng)
Alpha-Isomethyl Ionone
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Bisabolol
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Cholecalciferol, 1 Alpha,25 Dihydroxy
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Alpha-hydroxy acids, including polyhydroxy acids and bionic acids with alpha hydroxyl groups, and their salts
Health Canada
Health Canada Cosmetic Ingredient Hotlist
[Percutaneous absorption of drug from alpha-olefin oligomer gel bases].
Kaiho F, Hirose C, Shimizu A, Sunada K, Isoyama A et al.
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 1992
Effects of antioxidant polyphenols on TNF-alpha-related diseases.
Kawaguchi K, Matsumoto T, Kumazawa Y
Current topics in medicinal chemistry, 2011
Effects of antioxidant polyphenols on TNF-alpha-related diseases.
Kawaguchi K, Matsumoto T, Kumazawa Y
Current topics in medicinal chemistry, 2011
Effects of antioxidant polyphenols on TNF-alpha-related diseases.
Kawaguchi K, Matsumoto T, Kumazawa Y
Current topics in medicinal chemistry, 2011
Facile Fabrication of α-Bisabolol Nanoparticles with Improved Antioxidant and Antibacterial Effects.
Kim S, Yu S, Kim J, Khaliq NU, Choi WI et al.
Antioxidants (Basel, Switzerland), 2023
Effects of 1 alpha,25-dihydroxy-vitamin D3 and calcipotriol on organotypic cultures of outer root sheath cells: a potential model to evaluate antipsor
Limat A, Hunziker T, Braathen LR
Archives of dermatological research, 1993
Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha-hydroxy acid) for acne.
Liu H, Yu H, Xia J, Liu L, Liu GJ et al.
The Cochrane database of systematic reviews, 2020
α-(-)-bisabolol reduces pro-inflammatory cytokine product...
Anil K Maurya, Monika Singh, Vijaya Dubey, Suchita Srivastava, Suaib Luqman, Dnyaneshwar U Bawankule
Current pharmaceutical biotechnology, 2014
Uptake and bioconversion of alpha-tocopheryl acetate to a...
E P Norkus, G F Bryce, H N Bhagavan
Photochemistry and photobiology, 1993
Uptake and bioconversion of alpha-tocopheryl acetate to a...
E P Norkus, G F Bryce, H N Bhagavan
Photochemistry and photobiology, 1993
Uptake and bioconversion of alpha-tocopheryl acetate to a...
E P Norkus, G F Bryce, H N Bhagavan
Photochemistry and photobiology, 1993
Safety of alpha-arbutin and beta-arbutin in cosmetic products
Scientific Committee on Consumer Safety (SCCS)
European Commission — SCCS
Evaluation of the Synthesis and Skin Penetration Pathway of Folate-Conjugated Polymeric Micelles for the Dermal Delivery of Irinotecan and Alpha-Mango
Sirirak T, Subongkot T
Pharmaceutics, 2025
The Efficacy of Topical Cosmetic Containing Alpha-Arbutin...
Pimpa Tantanasrigul, Apinya Sripha, Bunchai Chongmelaxme
Journal of cosmetic dermatology, 2025
The Efficacy of Topical Cosmetic Containing Alpha-Arbutin...
Pimpa Tantanasrigul, Apinya Sripha, Bunchai Chongmelaxme
Journal of cosmetic dermatology, 2025
The Efficacy of Topical Cosmetic Containing Alpha-Arbutin...
Pimpa Tantanasrigul, Apinya Sripha, Bunchai Chongmelaxme
Journal of cosmetic dermatology, 2025
Corneal antinociceptive effect of (-)-α-bisabolol.
Teixeira GF, Costa FN, Campos AR
Pharmaceutical biology, 2017
Improvement of Skin Condition Through RXR Alpha-Activating Materials.
Ye S, Lee S, Kang S, Jun SH, Kang NG
Biomolecules, 2025
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR