Ascorbyl Tocopheryl Maleate
AKA “UNII-D2G6259XR5, D2G6259XR5, 2-L-ascorbyl 6-dalphatocopheryl 2-butenedioate, 320616-16-8, L-Ascorbic acid, 2-((2R)-3, 4-dihydro-2, 5, 7, 8-tetramethyl-2-((4R, 8R)-4, 8, 12-trimethyltridecyl)-2H-1-benzopyran-6-yl (2Z)-2-butenedioate), 2-L-ASCORBYL 6-D-ALPHA-TOCOPHERYL 2-BUTENEDIOATE, RefChem:114481, ASCORBYL TOCOPHERYL MALEATE [INCI], CME”
Emollient
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Ingredient Facts
Ascorbyl tocopheryl maleate
AKA: UNII-D2G6259XR5, D2G6259XR5, 2-L-ascorbyl 6-dalphatocopheryl 2-butenedioate, 320616-16-8, L-Ascorbic acid, 2-((2R)-3, 4-dihydro-2, 5, 7, 8-tetramethyl-2-((4R, 8R)-4, 8, 12-trimethyltridecyl)-2H-1-benzopyran-6-yl (2Z)-2-butenedioate), 2-L-ASCORBYL 6-D-ALPHA-TOCOPHERYL 2-BUTENEDIOATE, RefChem:114481, ASCORBYL TOCOPHERYL MALEATE [INCI], CME
Emollient · Antioxidant · EWG: 1
Synthetic
Antioxidant
Emollient
Skin Conditioner
Vitamin C
Clean
2-L-Ascorbyl 6-D-alpha-tocopheryl 2-butenedioate
Formula
C39H58O10
Mol. Weight
686.90
CAS #
320616-16-8
Form
Powder
See origin →
Functions
Antioxidant
Fights free radicals — the unstable molecules from UV, pollution, and stress that break down collagen and cause premature aging.
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Emollient
Fills in the tiny cracks between skin cells to make everything feel smooth and soft. The "silky finish" ingredient.
Locks In Moisture
Traditional Use
Synthesized as a dual-antioxidant compound pairing vitamin C and vitamin E via a maleate linker, developed to provide complementary free radical scavenging in modern skincare formulations.
Skin Types
●all-skin-types, gentle
Best For
Sun Damage
Pregnancy & Breastfeeding Safe
Yes
EWG
1
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
ewg-1
medical-approval
pregnancy-nursing-safe
all-shades-safe
Phototoxicity Concern
Concentration Guide
Dermal absorption: 1%. Source: CIR Safety Assessment (CIR Seq 667).
Regulatory Agencies
Final Report on the Safety Assessment of L-Ascorbic Acid, Calcium Ascorbate, Magnesium Ascorbate, Magnesium Ascorbyl Phosphate, Sodium Ascorbate, and Sodium Ascorbyl Phosphate as Used in Cosmetics
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Ascorbyl Tocopheryl Maleate
European Commission
EU Cosmetic Ingredient Database (CosIng)
Final report of the safety assessment of L-Ascorbic Acid, Calcium Ascorbate, Magnesium Ascorbate, Magnesium Ascorbyl Phosphate, Sodium Ascorbate, and
Elmore AR
International journal of toxicology, 2005
Final report of the safety assessment of L-Ascorbic Acid, Calcium Ascorbate, Magnesium Ascorbate, Magnesium Ascorbyl Phosphate, Sodium Ascorbate, and
Elmore AR
International journal of toxicology, 2005
Final report of the safety assessment of L-Ascorbic Acid, Calcium Ascorbate, Magnesium Ascorbate, Magnesium Ascorbyl Phosphate, Sodium Ascorbate, and
Elmore AR
International journal of toxicology, 2005
Final report of the safety assessment of L-Ascorbic Acid, Calcium Ascorbate, Magnesium Ascorbate, Magnesium Ascorbyl Phosphate, Sodium Ascorbate, and
Elmore AR
International journal of toxicology, 2005
Ascorbyl Tocopheryl Maleate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Topical L-ascorbic acid: percutaneous absorption studies.
Pinnell SR, Yang H, Omar M, Monteiro-Riviere N, DeBuys HV et al.
Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 2001
Topical L-ascorbic acid: percutaneous absorption studies.
Pinnell SR, Yang H, Omar M, Monteiro-Riviere N, DeBuys HV et al.
Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 2001
Topical L-ascorbic acid: percutaneous absorption studies.
Pinnell SR, Yang H, Omar M, Monteiro-Riviere N, DeBuys HV et al.
Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 2001
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR